What is the opposite of insignificant?

Need antonyms for insignificant? Here's a list of opposite words from our thesaurus that you can use instead.

Opposite of too small or unimportant to be worth consideration
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“A blood test will show a significant reduction in the hemoglobin content of the red blood cells and an increase in the size of the cells.”
Opposite of having no meaning or purpose
Opposite of not connected with or relevant to something
“At the risk of oversimplifying, the relevant questions can be gathered under three crude rubrics as the What, How, and Why questions.”
Opposite of not clearly visible or attracting attention
Opposite of of a minimum amount, quantity, or degree
“I was thrilled that I got the maximum marks on my end of year exams.”
Opposite of easily excused or forgiven
Opposite of not detectable or too small in magnitude to be observed
Opposite of very small
Opposite of of low social, administrative, or political rank
“Dad felt that my aristocratic heritage and working-class lineage would make me an ideal political candidate.”
Opposite of not famous
“Seizing the moment, she introduced herself to the famous film director.”
(outside chance) Opposite of small or improbable in degree
“There is a likely chance of a thunderstorm late tomorrow evening.”
Opposite of diminished or humiliated emotionally
“His boss praised him for his accomplishments and made him feel proud.”
Opposite of full of sorrow
Opposite of emphasizing insignificance
“Excelling at the firm often meant you would be relegated to positions of great influence.”
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