What is the opposite of insignificance?

Need antonyms for insignificance? Here's a list of opposite words from our thesaurus that you can use instead.

Opposite of something with little significance, or the state of being insignificant
Opposite of the state of being unknown, inconspicuous, or unimportant
Opposite of the condition of being mediocre, average or ordinary
Opposite of quality of being indistinct
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