What is the opposite of efficacy?

Need antonyms for efficacy? Here's a list of opposite words from our thesaurus that you can use instead.

Noun
Opposite of the ability to produce a desired effect or result
Noun
Opposite of the state or condition of being useful
Noun
Opposite of the benefit, importance or (useful) effect of something
“The insignificance of relaxation to stress relief is a myth. It is, in fact, crucial.”
Noun
Opposite of the effectiveness of an event or story
“Given the satirical clout of his greatest operettas, the charge of triviality now strikes us as absurd, but it rankled.”
Noun
Opposite of a quality considered good morally, or that gives something special worth
“His biggest failing is that he is willing to defend the King's transgressions, even when it is indefensible.”
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