The development of transgenic mice has opened up new possibilities for mutagenicity testing in small animal models. |
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And mutagenicity is of course a bad thing, because increased DNA damage is generally held to be a factor in carcinogenesis. |
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The residues were redissolved in DMSO for analysis of polynuclear aromatic compounds and for the mutagenicity test. |
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A high sulfur content of the fuel and high engine speeds and loads are associated with an increase in mutagenicity of diesel exhaust particles. |
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Our urine mutagenicity testing did not provide evidence of increased numbers of bacterial strain revertants. |
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Transgenic selection assays provide a unique opportunity to study the mechanisms of mutagenicity in different somatic and germinal tissues in vivo. |
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Additionally, monascus pigments, purpurin, chlorophyllin and curcumin were reported to inhibit the mutagenicity of heterocyclic amines and other carcinogens. |
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The mutagenicity dataset represents a binary classification problem where compounds are classified as mutagenic or non-mutagenic. |
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As Huff outlined, predicting carcinogenesis on the basis of chemical activity, such as mutagenicity, toxicity, or structural formula, is not a fully reliable methodology. |
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Many process intermediates are common across companies and sharing mutagenicity data on these compounds allows members to avoid duplicating costly and time consuming tests. |
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About two years ago, the NTP issued an interim warning that animal tests on both rats and mice indicated a strong probability of carcinogenicity and mutagenicity. |
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His current research interest is in the modulatory effects of natural products on the mutagenicity of direct and indirect acting mutagens and the genotoxicity of pesticides. |
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These results support the theory that As can act through a cocarcinogenic mechanism of action, exacerbating the genotoxicity and mutagenicity of other compounds. |
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Mutagenicity and carcinogenicity of benomyl and carbendazim. |
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