| In Southern blots, DNA is cut with restriction enzymes then separated. |
| The binding mechanism of psoralens to a double-strand DNA has been well investigated by chemical and enzymatic methods using restriction enzymes and exonuclease. |
| All constructs were verified by restriction enzymes analyses and sequencing. |
| Double-stranded oligos were multimerized using T4 DNA ligase in the presence of XhoI and SalI restriction enzymes to generate tandem arrays. |
| Eighteen candidate clones from the genomic library were digested with a series of restriction enzymes, Southern blotted, and hybridized with the same probe. |
| Biogen 1 discloses that the way to do it is to choose the restriction enzymes likely to cleave the Dane particle DNA into the largest fragments. |
