| It produces an antifibrinolytic effect through the reversible blockade of lysine binding sites on plasminogen molecules. |
| Five studies used streptokinase, two used urokinase, and four used tissue plasminogen activator. |
| The Borrelia need plasminogen from human blood to migrate to the tick's salivary glands and then infect the human. |
| All of these agents convert plasminogen to plasmin, which in turn breaks down fibrin and promotes clot lysis. |
| These observations add further support for a lack of thrombogenicity with heterozygous plasminogen deficiency. |
| Within the fibrinolytic system, plasmin is generated from plasminogen by tissue plasminogen activator, which upon activation lyses fibrin clots. |
