In this process the cell membrane engulfs portions of the external medium, forms an almost complete sphere around it, and then draws the membrane-bounded vesicle, called an endosome, into the cell. |
There is substantial experience of using photosensitiser compounds in therapy but not in terms of redeeming the molecule from the endosome. |
In an acidic environment, the membrane of an enveloped virus fuses with the endosome membrane, and the viral nucleocapsid is released into the cytoplasm. |
Movie 1: movement of a magnetic endosome on a fluorescent microtubule. |
They have found that if they inject photosensitisers into the patient at the same time as they inject the drug, the photosensitisers are absorbed into the membrane of the endosome. |
During endocytosis, the cell membrane on which the toxin sits gradually encircles the protein complex in an acidic sac or endosome. |