| During endocytosis, the cell membrane on which the toxin sits gradually encircles the protein complex in an acidic sac or endosome. |
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| There is substantial experience of using photosensitiser compounds in therapy but not in terms of redeeming the molecule from the endosome. |
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| Movie 1: movement of a magnetic endosome on a fluorescent microtubule. |
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| In an acidic environment, the membrane of an enveloped virus fuses with the endosome membrane, and the viral nucleocapsid is released into the cytoplasm. |
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| In this process the cell membrane engulfs portions of the external medium, forms an almost complete sphere around it, and then draws the membrane-bounded vesicle, called an endosome, into the cell. |
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| Under normal circumstances, NPC1, found within a cellular compartment called the endosome, helps bring cholesterol into the cell's cytoplasm, where it is necessary for healthy function. |
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| They have found that if they inject photosensitisers into the patient at the same time as they inject the drug, the photosensitisers are absorbed into the membrane of the endosome. |
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| Ebola, like many other viruses, first enters a cell's endosome. |
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