| Based on data with another glucocorticoid metabolized by CYP3A4, coadministration with ritonavir is not recommended because of the risk of systemic effects secondary to increased exposure to fluticasone furoate. |
| Caution should also be exercised when coadministration of modafinil and clomipramine is deemed necessary. |
| However, if coadministration with another vaccine is indicated, immunization should be carried out on separate limbs. |
| Research on the effects of coadministration of antimalarials and antiretrovirals is also of great interest but unfortunately lacking. |
| In conclusion, this study demonstrates that coadministration of ezetimibe and atorvastatin decreases sPLA2 activity. |
| If regular coadministration is required then alternative therapy must be considered. |
