| Those positions located in the catalytic core of the ribozyme are shown in italicized boldface type. |
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| Each of these ribozymes and a corresponding non-catalytic control ribozyme was cloned into the shuttle vector, pPCR-Script. |
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| A vector comprising a procaryotic promoter system and a ribozyme fused to a stable E. coli RNA gene which comprises from about 50 to 200 nucleotides. |
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| The plan is to use ribozyme to decrease the APP gene expression. |
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| Of these, only the hammerhead ribozyme form is in clinical trials as it offers advantages in manufacturing techniques. |
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| Integration of our in vitro-generated various ribozyme activities may lead to novel antibiotic synthesis through rational modular ribo zyme design. |
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| This sequence along with its immediate flanking sequences were used to generate a hammerhead ribozyme according to the Haseloff and Gerlach model. |
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| Ribozyme Pharmaceuticals Inc., Boulder, Colo., 3.2 million shares. |
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