| The dark appearance of the caudate nucleus and putamen is attributable to their content of blood vessels and neuronal cell bodies. |
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| Neuropathic itch occurs with any disease along the afferent neuronal pathway. |
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| Measuring metabolic and neuronal activity at the same time provides direct evidence for this link. |
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| Caffeine stimulates the central nervous system, thus increasing neuronal activity and brain function. |
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| Ecstasy alters neuronal function in a brain structure called the hippocampus, which helps create short-term memory. |
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| In case 3, however, we noted Purkinje neuronal drop-out, gliosis, and proliferation of microglial nodules in the cerebellar folia. |
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| Now he's looking to crowdfund his next research project, on the neuronal effects of amphetamines. |
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| These modulate the neuronal circuits that are thought to be dysfunctional in such disorders. |
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| Transsynapptic neuronal degeneration of optic nerves consequent to occipital lobe lesions is a rare phenomenon. |
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| Dissemination occurs in immunosuppressed individuals via hematogenous or direct neuronal extension. |
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| Gliosis is linked to neuronal degeneration and may explain the loss of the hypocretin cells. |
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| These processes are formed and maintained by the neuronal cytoskeleton, particularly microtubules and actin filaments. |
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| This primary pathology includes a range of inflammatory disorders as well as neuronal loss along with dendritic damage and synaptic loss. |
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| Non-drugged rats that were placed in the complex cages had spiny neurons with increased dendritic branching, reflecting new neuronal development. |
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| The synapse is the probable arena where general anesthetics depress neuronal function. |
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| The brain showed extensive neuronal loss and severe astrogliosis in the striatum and substantia nigra. |
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| Microinjection of bicuculline in the ventrolateral PAG led to a decrease in the neuronal responses to heat. |
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| The enteric nervous system contains a large number of neurons organized in intricate neuronal circuits. |
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| Because of the possibility of eventual neuronal death, the later neurologic consequences of pernicious anemia can be irreversible. |
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| Inhibitory interneurons participate in all neuronal circuits in the mammalian brain. |
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| Partial epilepsy results from abnormal neuronal activity that originates usually in one of the temporal lobes. |
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| Therefore, the homology of entomostracan and malacostracan neuronal stem cells remains uncertain. |
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| If aluminium causes direct neuronal death, why would this lead to slowing of conduction along the axons of the optic nerves? |
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| In contrast to neurocytomas, oligodendrogliomas do not demonstrate any features of neuronal differentiation, either by immunohistochemistry or electron microscopy. |
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| It's one sensory cell type and one neuronal cell type, and it's possible to do local delivery through the eardrum. |
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| This mutation yields two neuronal precursors rather than one, resulting in a subsequent increase in the number of neuroblast cells. |
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| Playing and practicing any sport at an elite level leaves in its wake broken bones, shredded ligaments and neuronal death. |
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| Actin dynamics and microtubule polymerisation can be monitored simultaneously in a living neuronal cell during polarization. |
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| Heuristic productive systems using fuzzy logic and neuronal networks for data collection and electrolytic process control. |
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| Histologic examination of the brain showed extensive neuronal loss, gliosis, rarefaction, scarring, and foci of chronic inflammation in multiple brain regions. |
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| The brain consists of millions of interconnected neurons, and cognitive activity reduces, ultimately, to patterns of neuronal excitation and inhibition. |
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| These abnormalities in the temporal lobe could be at the origin of autistic symptoms and also of a disorganisation of neuronal circuits. |
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| These problems can lead to neuronal loss and result in a wide range of disabilities such as reduced mobility, memory loss or impaired reasoning. |
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| However, increased aluminum exposure in people already developing amyloid plaques may hasten neuronal death. |
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| Variations in both genes cause an accumulation of proteins in the cytoplasm of neurons, which is suspected to contribute to neuronal dysfunction. |
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| Less known but just as important as the neurons, the glial cells provide nourishment and help to control neuronal activity. |
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| Histopathologic studies showed moderate neuronal degeneration characterized by neuronal hyperchromatosis, chromatolysis, and satellitosis. |
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| Our results indicate that persistent experience-dependent neuronal reverberation is a general property of multiple forebrain structures. |
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| The absence of FMRP in astrocytes may contribute to the abnormal neuronal structures seen in the brains of Fragile X patients. |
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| The only change that occurs in the brain is a reorganization of preexisting neuronal networks. |
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| Recent studies have investigated the source and target neurons for the diffusible neuronal messenger molecule nitric oxide in the nervous system of the locust. |
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| But this functional lateralization is difficult to explain in terms of neuronal circuits. |
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| This Institute brings together for the first time the basic neurosciences with psychiatry and neurology to investigate the fundamental neuronal basis of mental illness. |
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| One such protein that cues neuronal function and survival is brain-derived neurotrophic factor or BDNF for short. |
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| The local microenvironment regulates neuronal regeneration through the astrocytic syncytium. |
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| T lymphocytes and B lymphocytes impact neuronal repair when activated by a variety of stimuli. |
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| Each microstate corresponds to a particular configuration of neuronal activity in the brain. |
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| It is possible to delay the effects, but it is not yet possible to prevent progressive neuronal loss. |
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| At autopsy, the brain showed mild basal ganglia atrophy and substantia nigra depigmentation, with extensive striatal and substantia nigral neuronal loss and astrogliosis. |
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| Neurosteroids can therefore alter neuronal excitability very rapidly by binding to receptors for inhibitory or excitatory neurotransmitters at the cell membrane. |
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| Our lab continues to investigate neuronal death and it's relationship to endothelial activation after cerebral ischemic-reperfusion injury. |
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| We analysed eye movements and neuronal firing in the abducens nucleus. |
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| This substance stimulates neuronal activity in a specific region of the prefrontal cortex and could give rise to a new class of anti-depressants. |
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| Gliosis, vascular proliferation and neuronal degeneration may be present in the brain. |
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| An abnormality of neuronal differentiation in the nuclei involved in respiratory control. |
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| Homocysteine also causes DNA strand breakage, resulting in mitochondrial membrane damage, nuclear disintegration, and apoptosis of neuronal cells. |
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| Cell shape change is fundamental to diverse processes including gastrulation, neuronal pathfinding, immune response, metastasis, and cytokinesis. |
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| In the brain, zinc is stored in specific synaptic vesicles by glutamatergic neurons and can modulate neuronal excitability. |
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| Rufinamide exhibits its anticonvulsant effects through limiting neuronal sodium-dependent action potential firing. |
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| Gyration and sulcation occur during neuronal migration and continue until after birth. |
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| Vectorial cerebral hemisphericity involves the interplay of neuronal firing between the cerebral hemispheres of the brain. |
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| For my post-doctoral research, I switched my attention from the glial factors that restrict neuronal growth to the neuronal changes that could explain why neuronal plasticity decreases as the brain maturates. |
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| While accumulating evidence shows that resting microglia respond to neural activity, we surprisedly noticed that resting microglia can also in turn regulate neuronal activity. |
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| The brain has a chance during sleep to shut down and repair neurons and important neuronal connections that might otherwise deteriorate due to lack of activity. |
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| This loss must be temporary, however, or the animal would become more amnesic with each hibernation. The brain stores information in neuronal networks. |
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| Sustained neurological disability is believed to be due to transection of neuronal processes within affected brain regions and subsequent failure of neuronal processes to repair themselves. |
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| Steroid hormones affect neuronal excitability. |
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| As with all local anesthetics, the dosage varies and depends upon the area to be anesthetized, vascularity of the tissues, number of neuronal segments to be blocked, individual tolerance and the technique employed. |
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| In 1988, a pioneering discovery by Story Landis indicated, in rodents, that neuronal phenotype is directed by retrograde signals secreted from the target cells that the neurons innervate. |
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| The persistence of chromosomal aberrations was related to the decrease in proliferative activity of neuronal tissue in the early period after birth. |
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| Posology: 20 ml ampulla to be taken orally Action mode: The Calcium lactate Pronarcolep has a modulating effect on neuronal inhibition in which the GABA mediates. |
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| Davidson's team focused on the rare, inherited childhood disorder, late infantile neuronal ceroid lipofuscinosis, also called Batten disease. |
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| It is the most common form of a group of disorders called neuronal ceroid lipofuscinosis. |
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| The novel neuronal ceroid lipofuscinosis gene MFSD8 encodes a putative lysosomal transporter. |
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| Secobarbital attenuates excitotoxicity but potentiates oxygen glucose deprivation neuronal injury in cortical cell culture. |
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| The first line investigates the neuronal mechanisms underlying auditory sensory memory trace formation. |
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| The level of activity of GABA mediated neurotransmission modulates the excitability of target neurons, thereby shaping the activity of neuronal networks in relation to the behavior. |
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| Pyrethroid insecticides bind to voltage-gated sodium channels and modify their gating kinetics, thereby disrupting neuronal function. |
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| Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS syn aptogenesis. |
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| There are two main types of exotoxins produced by Clostridium: enterotoxins, which exert their actions on the enteric cells of the gastrointestinal tract, and neurotoxins, which cause neuronal dysfunction. |
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| The idea is that the neuronal excitement in the brain that produces seizures can be altered, aborted or prevented by teaching a patient to change their state of arousal with the help of a particular aroma. |
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| The dynamic exchange of these progenitor-specific subunits for the homologous BAF45b, BAF45c and BAF53b subunits during neural development is essential for cell cycle withdrawal and the acquisition of neuronal properties. |
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| This includes disorders like neuronal degeneration and trinucleotide repeat disease. |
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| Llansola et al. 1999: Decrease in pup body weight, decreased number of cells in cerebellum, disaggregation of microtubules and neuronal death in cerebellar neuron cultures. |
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| In this paper, we have considered the somatic nervous system of the nematode Caenorhabditis elegans, for which the entire neuronal connectivity diagram is known. |
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| Schwann cell, also called neurilemma cell, any of the cells in the peripheral nervous system that produce the myelin sheath around neuronal axons. |
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| Neurodegenerative disorders are characterized by progressive neuronal loss and the aggregation of disease-specific pathogenic proteins in hallmark neuropathologic lesions. |
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| In 1907 Italian biologist Emilio Lugaro suggested that neuroglial cells exchange substances with the extracellular fluid and in this way exert control on the neuronal environment. |
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| After high levels of neuronal activity, for instance, neuroglial cells can take up and spatially buffer potassium ions and thus maintain normal neuronal function. |
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| Results revealed cytoarchitectural distortion and extreme chromatolysis in neuronal cells of the cerebellar cortical layers in the nicotine-treated group. |
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| Beneath the photoreceptor cells there are usually three ganglionic layers the lamina, the medulla, and the lobula that form a set of neuronal relays, and the rhabdom is connected to these layers by a single axon. |
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| Thus, the mechanical compression of bone tissues and the algogenic substances released by the bone environment and tumor at day 8 are not sufficient to exacerbate nociceptors and stimulate abnormal neuronal firing. |
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| Caspase-9 was later demonstrated to reside in the mitochondria of cardiomyocytes and neuronal cells, however only neuronal cell ischemia in an animal model was examined. |
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| Multiple sclerosis is characterized by demyelination and neuronal damage as a result of infiltration of activated immune cells into the central nervous system. |
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| That, in turn, causes the neurons to begin to die back, leading to reduced transmissions, more dying back and eventual neuronal cell death. |
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| Diazepam-its effects on the development of pentylenetetrazol kindling, related learning impairments, and neuronal cell loss. |
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| Such elucidation of neuronal circuits is of critical importance but less well known, and of equal importance for future progress, are the spectacular advances of the 1990s in psychopharmacology. |
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| Expression was strongest in the epidermis of the procephalic lobes and labrum, and no staining was found within cephalic and labrum regions where the neuronal cells are present. |
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| As the increase in flow exceeds the increase in oxygen consumption, neuronal activity is expressed as a relative increase in oxyhemoglobin compared to deoxyhemoglobin in the activated zones. |
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| This project aims to automate the processing of neuronal signals recorded by doctors to detect any malfunctioning of neurons in the brain or motoneurons that control muscle fibres. |
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| This symposium included sessions focused on the mechanisms of patterning, organogenesis, neuronal determination and synaptogenesis, stem cells and molecular mechanisms of human disease. |
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| He is ashamed of the age difference: For months, my bedtime stories had spun a decameron of long-term potentiation, recategorizing, neuronal group selection, transmitter and junctional molecules. |
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| After mercury changes in the environment to methylmercury, the most toxic form, it readily crosses the blood-brain barrier and can cause severe neuronal damage. |
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| Early reports of loss of cholinergic neurons and associated neuronal markers fuelled interest in the role that these neurons play in Alzheimer disease, and in deficits in memory and attentional processes. |
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| Patients also may undergo electromyography, which records the electrical activity of muscle fibres, and nerve conduction studies, which measure the speed of neuronal conduction and the strength of neuronal signaling. |
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| Researches and studies proved that water low in magnesium can cause increased morbidity and mortality form cardiovascular disease, higher risk of motor neuronal disease, pregnancy disorders, preeclampsia. |
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| Until I read the Science Times article, I had never actually heard of anyone using the excimer laser for brain surgery, either on neuronal or vascular tissue. |
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| Complementary molecular, cellular and imaging techniques are used to evaluate gene expression, cell phenotype, intercellular communication and integration of neuroimplants into the brain neuronal network. |
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| Cell proliferation in the cerebellum and olfactory bulbs was comparable to that in untreated controls, as were migration and aggregation of neuronal cells in the cerebral cortex. |
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| Whether the emotion triggered by an advertisement is positive or negative, the brain tonsil acts as a catalyst to strengthen the neuronal connections. |
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| The findings, reported in the journal Stem Cell Reports, indicated that defective GRN altered the Wnt signalling pathway, which plays an important role in neuronal development. |
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| The former work on analysis, optimisation and visualisation programmes for data, while the latter investigate the anatomy, morphology and functions of neuronal cells. |
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| It would seem, however, to have an affect on the neuronal mechanisms and on the efficiency of antidepressants, though this remains pure assumption. |
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| This system can be adapted to screen libraries of chemical compounds and discover novel molecules with guidance activity that could find applications in neuronal regeneration. |
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| Once inhaled, an odorant is bound by these receptors, which trigger a cascade of events, ultimately leading to a pattern of neuronal signals in the brain, characteristic for the perceived odour. |
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| Genetics have been particularly fertile in the area of the neurosciences, revealing families of genes for the enzymes, receptors and linking proteins which take care of the different neuronal functions. |
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| It degrades the myelin sheaths of neurons, reduces their numbers, interferes with neurotransmission routes, and decreases neuronal growth. |
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| In the brain the clear cells represent the accumulation of gangliosides and are often associated with significant neuronal loss and gliosis. |
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| The group analyses the molecular regulation of neuronal dendritic tree formation during early development of the mouse neocortex. |
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| This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. |
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| Chronic cerebral hypoperfusion elicits neuronal apoptosis and behavioral impairment. |
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| Their mechanism of action for cholinergic enhancement is suboptimal, and they do not repair neurons, protect against death, or truly restore lost neuronal function. |
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| It is a selective neuronal nicotinic receptor antagonist and the S-isomer of mecamylamine, a drug previously marketed for use in resistant hypertension. |
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| Neuroblast proliferation is essentially complete before 28 weeks, whereas neuronal migration and aggregation continue through the first half of the third trimester. |
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| More specifically, in connectionism neurons are modelled as units and neuronal synapses are represented by the connections between nodes or weights. |
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| They discovered that the number of spiny structures located at the neuronal synapses was significantly lower in rats that had copulated, New Scientist reported. |
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| The biochemical events within the CTZ neurons that convert chemical stimuli into the neuronal signals that induce nausea and vomiting are poorly understood. |
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| However, modifications of these cells due to the movement of the endolymph in the inner ear, results in a change in the tonic neuronal firing rate. |
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| Tonabersat is a first-in-class neuronal gap junction modulator that may have applicability in a variety of neurological conditions, including migraine and epilepsy. |
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| Agyria or pachygyria as well as a thickened cerebral cortex are seen on imaging studies, differentiating lissencephaly from malformations of neuronal proliferation. |
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| Most studies addressing the underlying mechanisms at the level of neuronal circuits have focused on aversive learning, such as in Pavlovian fear conditioning. |
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| The distal tier of cells has a wider acceptance angle than the proximal tier and different neuronal wiring, as well as a different spectral receptor composition. |
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| Immunoreaction took place mostly in neuronal soma, but not in nuclei. |
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| Transient global cerebral ischemia in Mongolian gerbils was used to investigate the OLE effects on different parameters of oxidative stress and neuronal damage in hippocampus. |
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| Martin's group recently reported that they were able to produce the Huntington's pattern of neuronal destruction by injecting the excitotoxin quinolinic acid into rat brains. |
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| Human chorionic gonadotropin induces neuronal differentiation of PC12 cells through activation of stably expressed lutropin choriogonadotropin receptor. |
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| The excitotoxicity produced by abnormal levels of glutamate is thought to be responsible for the neuronal cell dysfunction observed in Alzheimer's disease. |
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| Within the experiment, the conversion method was used to convert fibroblast cells back into induced neuronal progenitor cells after converting it back to its stem cell stage. |
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| In the cerebral cortex, excitatory glutamatergic pyramidal cells and inhibitory interneurons constitute the main cellular elements of neuronal circuits. |
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| By blocking this co-transporter with bumetanide, a loop diuretic, the depolarizing action of GABA will be reversed resulting in reduced neuronal firing. |
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| The most common pathological features of GSS include numerous amyloid plaques, spongiform changes, neuronal loss, astrocytic microgliosis, and neurofibrillary tangles. |
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| Their results revealed that subsets of neurons expressing thyrotropin-releasing hormone and pituitary adenylate cylcase-activating polypeptide were in on the neuronal chatter. |
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| Neurons fired in a pattern resembling human neuronal patterns. |
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