| In 1868, Charcot identified neuropathic joints with an unusual pattern of bone destruction in patients with tabes dorsalis. |
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| In fact, we owe much of what we know about managing neuropathic foot ulcerations related to diabetes to Dr Brand's pioneering work. |
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| I am being treated with some anti-epilepsy drugs that have some success in treating neuropathic pain. |
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| The spasms of multiple sclerosis and resistant neuropathic pain are two obvious targets. |
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| A muscle biopsy confirmed neuropathic changes in a pattern consistent with denervation. |
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| However, the purpose in inserting the stimulator is to dampen or reduce continuous neuropathic pain which is pain derived from nerve structures. |
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| Tricyclic antidepressants or anticonvulsants, often given in low dosages, may help to control neuropathic pain. |
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| Loss of pain sensation together with possible rarefaction of the bones of the neuropathic foot can have serious consequences. |
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| About 86 percent of those with multiple sclerosis suffer from neuropathic pain, or nerve pain, a common symptom of the disease. |
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| This individual initially presented from the community with a painful, sloughy, neuropathic ulcer. |
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| It is a short term study, involving 32 clinical subjects to evaluate the effects of smoked marijuana for chronic neuropathic pain. |
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| Simulated work performance tasks in persons with neuropathic and myopathic weakness. |
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| The morphological changes that take place differ in myopathic and neuropathic conditions. |
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| The type of wound with the clearest indication for aggressive off-loading is a neuropathic wound on a weight-bearing area on the sole of the foot. |
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| Mixed pain in many instances is a combination of nociceptive and neuropathic pain. |
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| An important factor in neuropathic pain is muscle shortening, caused by muscle spasm and contracture. |
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| Others still might suffer delusions in addition to their undiagnosed neuropathic illness. |
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| Physicians should continually educate their patients about the proper care of a neuropathic foot and the use of orthotic devices or custom footwear. |
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| Methadone's unique pharmacokinetics and pharmacodynamics make it a valuable option in the management of cancer pain and other chronic pain, including neuropathic pain states. |
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| Her MS is extremely advanced, to the point where she experiences daily neuropathic pain that renders her to only 2 to 3 useable hours a day. |
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| It seeks to discover new medicines to treat common disorders, such as neuropathic pain and epilepsy. |
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| It is also used to treat essential tremor, bulimia nervosa, obsessive-compulsive disorder, alcoholism, smoking cessation, neuropathic pain, etc. |
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| This submission to the Common Drug Review relates solely to its use in diabetic peripheral neuropathic pain. |
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| The commonest cause of neuropathic ulceration is diabetes, and many diabetic patients with neuropathic ulceration will also have an arterial problem that requires correction. |
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| Similarly, there are currently no pharmacological substances able to suppress neuropathic pain. |
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| Functional deficiency occurring during the leg lengthening has neuropathic, myopathic and arthropathic aspects. |
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| What would you choose as the drug of first choice to promote healing and lessen the neuropathic pain? |
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| If given in controlled doses, modern opiates can be an effective treatment for neuropathic pain and other forms of chronic pain. |
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| A therapeutic composition comprising a neuropathic pain alleviating amount of a mixture of dextromethorphan and dextrorphan or the pharmaceutically acceptable salts thereof, further comprising a local anesthetic. |
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| Disk herniation with radicular pain is one example of neuropathic disease. |
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| Pharmacological treatment of neuropathic pain may start with a simple painkiller, namely acetaminophen, aspirin or non-steroidal anti-inflammatories. |
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| It can be used to treat chronic pain, reduce neurotoxicity and assist with neuropathic conditions. |
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| The most common cause of nerve irritation and neuropathic pain is «spondylosis», degeneration in the spine, which can be the result of normal wear and tear. |
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| In addition to the treatment of stress urinary incontinence in women, duloxetine is also currently being developed for the treatment of depression and diabetic neuropathic pain. |
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| As duloxetine is also approved for the treatment of major depressive disorders, drug plans should ensure that reimbursement is confined to patients with diabetic peripheral neuropathic pain. |
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| Long-term safety data of duloxetine in the management of diabetic peripheral neuropathic pain beyond 12 weeks has not been assessed in controlled trials. |
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| Pregabalin works presynaptically on overactive calcium channels and can reduce the symptoms of neuropathic pain. |
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| A history of significant trauma, cervical arthritis, prior herniated disk or herpes zoster infection, along with typical neuralgic pain and sensory disturbances, should suggest a neuropathic process. |
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| Smoked cannabis has been evaluated in a small number of randomized controlled trials involving patients suffering from neuropathic pain conditions. |
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| I broke my leg last year, and it took me and my physical therapist a week to realize it, because my broken leg was unremarkable compared to my chronic neuropathic pain. |
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| What are the first-line treatment options for neuropathic pain? |
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| Ataciguat is still being developed as a treatment for neuropathic pain. |
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| We found that nerve cells in the spinal cord, which normally form a filter of sorts, act as an amplifier of pain signals in the neuropathic state. |
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| Typically these treatments should be of last resort and only after extensive and thorough diagnosis in conjunction with full mouth and neuropathic assessments. |
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| In an epidemiology study, 44 percent of patients suffered from a mix of neuropathic and nociceptive pain. |
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| Use carbamazepine, gabapentin, or lamotrigine for neuropathic pain instead of the more toxic tricyclic antidepressants. |
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| Bicifadine is a first-in-class triple reuptake inhibitor for the treatment of diabetic neuropathic pain. |
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| Now, a report from an expert panel published in the journal PAIN presents a consensus approach to assessing the phenotype of neuropathic pain. |
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| Nicknamed arylmethylidene heterocycle, the formula aspires to be a neuropathic pain reducer someday. |
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| In addition, mexiletine and transdermal lidocaine have shown benefit for neuropathic pain states as well. |
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| Mexiletine is a local anesthetic, taken by mouth, which is similar to lidocaine and has been studied in symptomatic management of neuropathic pain of various ideologies. |
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| The first symptoms are paresthesias, with dysesthesias occurring after a few courses of chemotherapy, and often followed by severe neuropathic pain. |
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| Chronic pain is classified as nociceptive pain and neuropathic pain. |
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| Research on the genetic factors contributing to neuropathic pain has been hindered by the lack of a standard approach to assessing its clinical characteristics or phenotype. |
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| Neuropathic itch occurs with any disease along the afferent neuronal pathway. |
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| Neuropathic pain is present in 55 per cent of all cases of chronic low-back pain, making it more common than nociceptive pain, said a study. |
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| Neuropathic pain is caused by lesion or disease of the somatosensory nervous system. |
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| Neuropathic pain is a frequent complication of spinal cord injury. |
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| Neuropathic foot ulceration in patients with myelodysplasia. |
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| Neuropathic arthropathy progressing with multiple joint involvement in the upper extremity due to syringomyelia and type I Arnold-Chiari malformation. |
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