How to use melanoma in a sentence

Looking for sentences and phrases with the word melanoma? Here are some examples.

Sentence Examples One form of skin cancer, malignant melanoma, can spread to other organs very rapidly. Common benign lesions that mimic melanoma include seborrheic keratoses, benign acquired nevi and solar lentigenes. The tumor was composed of spindle and epithelioid cells, some of which were arranged in a fascicular pattern, consistent with malignant melanoma. The dangers of sun worshipping, such as malignant melanoma and accelerated ageing, are well known. Malignant melanoma is the least common yet most dangerous form of skin cancer. The commonest malignancies are basal cell carcinoma, squamous cell carcinoma, and melanoma. Choroidal melanoma is a tumor of the eye that forms from pigmented cells of the choroid, a layer of vascular tissue in the back of the eye. Sun exposure in childhood and having more than one blistering sunburn in childhood are associated with an increased risk of melanoma. The ultraviolet rays emitted by tanning beds can damage skin and cause wrinkles, age spots, and even lead to skin cancer such as melanoma. Severe sunburn in childhood can significantly increase the chances of developing malignant melanoma in later life. Patients with melanoma require close follow-up because they are at risk for recurrence and diagnosis of a second primary tumor. Some cases have a family history of melanoma, suggesting a genetic contribution. Instead they can look forward to suntans, palm trees, olive groves, melanoma and malaria. A systematic study was carried out to evaluate its antitumour efficacy against B16 murine melanoma. She had beaten off the disease five years ago after a melanoma had been found on her leg. It should be noted that regional lymph node involvement is rare in uveal melanoma. Spindled dermal melanoma cells, with or without neurotropism and desmoplasia, are also seen in this variety. Therefore, nodular amelanotic melanoma is the most important tumor to differentiate from pyogenic granuloma. Investigators assume that ultraviolet light is the most important factor for the initiation of malignant melanoma. A lot of that's just an assessment of his general medical condition and not necessarily germane to the melanoma itself. Show More Sentences The most predictive features for melanoma development are a history of change in an existing nevus or a new and changing pigmented lesion. Thomas and Patocskai may see no advantage in staging disease in patients with melanoma, but theirs is a minority view worldwide. It is extremely difficult to prove that a malignant melanoma originates in a visceral site. The echocardiography and the pathologic examination revealed a metastatic melanoma. We report a case in which cutaneous metastases from a melanoma imitated herpes zoster. Metastases from cutaneous melanoma normally present as flesh coloured papules or nodules in the skin. Persons who have a tendency to burn and freckle rather than tan also have an increased melanoma risk. Malignant melanoma can also affect the choroid of the eye, the layer just under the retina. It is also known that melanoma, a potentially fatal skin cancer, is associated with blistering sunburns in childhood. Any mole that is suggestive of melanoma requires an excisional biopsy, primarily because prognosis and treatment are based on tumor thickness. Ocular melanoma metastatic to other sites generally occurs in association with liver metastases. Patients are also at risk for cancers of the brain, lung, stomach, tongue, and melanoma of the eye, and leukemia. One severe sunburn early in life doubles the chances of future malignant melanoma. Malignant melanoma is commoner in later life but many young adults are also affected. Lentigo maligna melanoma is where a patch of lentigo maligna develops a papule or nodule signalling invasive tumour. Changes to deep-black colour and elevation or slight infiltration suggest lentigo maligna melanoma. The development of an elevated nodule within the area of pigmentation indicates the change to vertically invasive lentigo maligna melanoma. Slow-growing variant of melanoma arising in a premalignant lesion, lentigo maligna, which appears on the sun-exposed skin of elderly people. Drawing direct lines from tanning bed to melanoma can be complicated, depending on people's other risks. One of the most important warning signs for melanoma is rapid change in a nevus or the appearance of a new black lesion. Show More Sentences These antigens stimulate T-cells within the immune system to hone in on melanoma cells, thereby halting or slowing cancer growth. After being sent to the eye doctor the diagnosis was that he had a melanoma tumor in his eye. Generally appearing as a blackish mark, melanoma is a tumour that develops in the melanocytes. A punch biopsy at the border of the lesion is necessary to rule out melanosis secondary to malignant melanoma that manifests as a generalized blue-gray skin discoloration. Usually made on clinical findings, at times confirmed by excision and dermatopathologic examination to rule out nodular melanoma. Differentiation from nodular malignant melanoma may require the help of a dermatopathologist who is familiar with pigment-cell neoplasms. Two guests will be on hand to answer questions about their personal experiences with melanoma skin cancer. Malignant melanoma is the most serious form of skin cancer as metastasis can occur early and it reason a number of deaths even in young people. Developed by Merck, pembrolizumab will be used to treat advanced melanoma, a skin cancer. The shadows are tumours from secondary melanoma, one of the most aggressive cancers known. Halos can be seen as part of a more generalized pigment loss, vitiligo, or in melanoma. The same happens with melanoma or skin cancer, the incidence of which is rapidly increasing. This does not include skin cancer, but it does include malignant melanoma, Stage II or higher. It may also lead to accelerated ageing of the skin and might increase the risk of both non-melanoma and melanoma skin cancers. When detected early, however, most cases of melanoma can be successfully treated. Such findings are considered to be a strong indication for biopsy of the nail matrix to rule out melanoma. Further, the policy exclusion for melanomas of the skin with reference to Clark Level staging does not apply to choroidal melanoma. Ocular melanoma is one example of a tumor that can be treated with LDR brachytherapy. A virtual navigation pilot program for melanoma and colorectal cancer patients was evaluated at numerous cancer centres across Canada. He has a bulbous-shaped face brought on by a combination of old age and his struggle with melanoma. Show More Sentences These suspicious lesions need to be biopsied, that is have tissue removed for microscopic diagnosis, and in melanoma the biopsy should include complete removal. Finally, the numbers of radio stations that were locally receivable were correlated with the melanoma incidence for the 288 communities in Sweden. It is also important to remember that a melanoma can undergo spontaneous regression and may not be detected, despite a thorough physical examination. The effects of sunlamps and tanning beds on the risk for melanoma are unclear due to limited study design and conflicting results from retrospective studies. An upward trend is especially apparent in kidney, liver, and thyroid cancer and in melanoma and lymphoma. The worst survival was for patients with cutaneous, monocular melanoma. Some recent research into the causes of malignant melanoma in adults suggests that getting badly sunburned as a child might have something to do with it. A 54-year-old man with rheumatoid arthritis presented for excision of an infrascapular melanoma and sentinel lymph node biopsy. Most probable therapeutic applications include blood cancer such as leukemia and lymphomas as well as solid tumors such as melanoma, breast and colon cancers, which affect more than 1.6 million people worldwide. Malignant melanoma originates in the pigment forming cells in the skin or, more rarely, in the mucous membrane, the choroids of the eye or the cerebral membranes. The main risk factors for the development of melanoma are increased naevus numbers, previous melanoma, strong family history. Non-antigen-specific immunotherapies such as immunocheckpoint blockades have been shown to be effective in the treatment of advanced melanoma. For iris and iridochoroidal melanoma, paraffin-embedded tissue sections were retrieved from the pathology department. People who consume more orange juice and grapefruit have a higher risk of melanoma skin cancer, says a new study. Cathepsins B, H, L, their inhibitors stefn A and cystatin C in sera of melanoma patients. More effective versions are being brought to bear on melanoma. Hematospermia as the presenting symptom of metastatic malignant melanoma of unknown primaiy origin. Psoralens interact with ultraviolet light to stimulate the proliferation of melanoma cells. The differential diagnosis includes high-grade liposarcoma, leiomyosarcoma, rhabdomyosarcoma, melanoma, carcinoma, and lymphoma. To test that theory, the researchers first injected mice with a solution of cancer cells, either melanoma or fibrosarcoma. Show More Sentences Contact radiotherapy offers a comfortable alternative to enucleation when size and location of an ocular melanoma make transpupillar heat therapy impossible. Optimal surgical therapy in the management of anorectal melanoma is uncertain and controversial. Inhibitory effect of Cordyceps sinensis on spontaneous liver metastasis of Lewis lung carcinoma and B16 melanoma cells in syngeneic mice. Perry had arthritis, two melanoma removal surgeries, and bad hipbone replacement. Studies of people with Parkinson's disease show that they may be at an increased risk of developing melanoma, a form of skin cancer, when compared to people without Parkinson's disease. The pharmaceutical and vaccine arms of the sanofi-aventis Group are working together on the development of therapeutic vaccines for colorectal cancer and melanoma. The proposal aims at setting up melanoma models in order to investigate the role played by the microenvironment in the occurrence and the progression of the tumor process in melanoma. A portion of the observed threefold increase in melanoma cancer rates in Canada between 1969 and 1992 is believed to be the result of ozone depletion. The role of the sun in the aetiology of malignant melanoma is controversial. Slowly growing premalignant disease due to proliferation of atypical melanocytes within the epidermis, which can progress to lentigo maligna melanoma. Studies show that too much exposure to the sun during childhood, in particular frequent painful sunburn, could represent a factor of risk in getting a melanoma as an adult. An important and new therapeutic concept for melanoma is to target the melanocyte lineage. The mutations in melanoma cells occurred in parts of the melanocyte genome that are normally turned off. For instance, the skin cancer melanoma arises from pigment-producing cells called melanocytes. David Chu, section chief of the division of melanoma and surgery at City of Hope National Medical Center in Duarte. Other risk factors include atypical mole syndrome, giant congenital melanocytic naevi, lentigo maligna and a positive family history of malignant melanoma. In fact, some international studies have found that the greatest rise in melanoma occurred in countries where chemical sunscreens were heavily promoted. However, in recent years, a number of breakthrough treatments that can potentially significantly improve the prognosis for some people with malignant melanoma have become available. Overusing sunbeds and sunlamps may also increase your risk of developing melanoma. Excesses in several cancers, such as melanoma, testis and Kaposi sarcoma, appear to contribute to the overall higher rate in the US white SEER population. Show More Sentences Experts found drinkers have a 20 per cent increased chance of melanoma compared with non-drinkers or occasional tipplers. So if you see lack of uniformity, think of things like atypical nevi, dysplastic nevi, or melanoma. Melanocytes form nevi and from the nevi melanoma can develop through mutations in various genes. Because of the presence of architectural maturation and fibrotic surrounding stroma, nevoid melanoma may also resemble hyalinizing Spitz nevus. They concluded that PHH3 and Ki-67 can be useful adjuncts to histopathology to separate malignant melanoma from benign nevus. Additionally, it has also been reported that it can overlie some benign and malignant lesions, including some nevi, melanoma and neurofibroma. Acral melanoma is a type of skin cancer that occurs on fingers, palms, soles, and nail beds. The final objective is to highlight new mechanism in melanoma progression and to open new ways for the prognostic and the treatment of this pathology. In a paper published recently by Toxicon, they report how a protein called eristostatin, which can be extracted from the venom of the Asian sand viper, helps people's immune systems fight malignant melanoma. The case was reevaluated and reconsidered as a primary palatine tonsillar achromic melanoma with concomitant pigmented gastric and ileal metastases. A number of conditions can cause longitudinal melanonychia, but its main importance is that, in some patients, it may indicate the presence of a subungual malignant melanoma. Her medical history revealed a multinodular goiter, stage 1 melanoma cancer, and Caesarean section. The rarity of our case is the presence of amelanotic melanoma in palatine tonsil. Excessive melanin production occurs in melasma, lentigo, nevocellular nevi and malignant melanoma, whereas the loss of melanocyte function leads to vitiligo. To appropriately consider the concept of melanoma vertical growth, it is important to first understand the nature of what antecedes it in most melanomas, namely radial growth. In addition, the company has obtained worldwide exclusive license for an emerging melanoma diagnostic and prevention technology utilizing Electron Paramagnetic Resonance. Similar to BRAF and MEK inhibitors, ganetespib effectively suppressed the activity of ERK kinase in melanoma cells, a critical component in the BRAF signaling cascade. All cell lines are of human origin and include U373 and T98G glioblastoma, LoVo colon cancer, a549 prostate cancer, OE21 esophagal cancer and SKMEL-28 melanoma cell lines. The inhibition of tyrosinase can play a key role in the management of diseases such as cutaneous hyperpigmentation disorders such as lentigines, and possibly melanoma. Histological examination with haemotoxylin and eosin staining was interpreted by the pathologist to be consistent with a 6 mm deep, Clark's level 5 melanoma. Show More Sentences Bowen's disease, Paget's disease, and malignant melanoma in situ. This finding suggests melanistic hyperplasia, due to nevi or melanoma. The differences of the fitting curves for the two indicators further highlighted the nonmonotonic dependence of cutaneous melanoma and UVA exposures. Spindle cell melanoma is a rare morphologic variant of melanoma. Since then, a large handful of small-cap Dendreon-like cancer immunotherapy companies have pursued related immunotherapies to combat breast, melanoma, brain and other cancers. Her study focused on basal cell and squamous cell carcinomas, which are less dangerous than melanoma but, if untreated, can be disfiguring or even lethal. The patient's medical history was significant for diabetes, hypertension, hyperlipidemia, hemorrhoidectomy, and a cutaneous melanoma excised from his back 8 years earlier. Examples from Classical Literature Histopathology is just another predictor among other known prognosticators of complex malignancies like melanoma. Find more words! 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What is the opposite of melanoma? Words that rhyme with melanoma What is the plural of melanoma? What is the adjective for melanoma? What is the noun for melanoma? Translations for melanoma Use our Sentence Generator Nearby Words melanogenesis melanogaster melanocytes melanocyte melanization melanite melanomas melanosis melanotic Melany melas melasma 8-letter Words Starting With m me mel mela melan melano melanom