| We report on two women with hyperbilirubinaemia caused by druginduced hepatotoxicity in early pregnancy. |
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| Many patients on ATZ experience indirect hyperbilirubinaemia, which causes social discomfort but does not necessitate a therapeutic change. |
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| Severe hyperbilirubinaemia, or failure to respond to phototherapy, may require exchange blood transfusion. |
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| As toxicity progresses, centrizonal hepatocellular injury may develop, manifesting as hepatocellular enzyme elevation and hyperbilirubinaemia. |
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| As well as biliary atresia, there are many other causes of conjugated hyperbilirubinaemia. |
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| It may induce haemolytic anemia, hyperbilirubinaemia and phototoxicity. |
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