| We report on two women with hyperbilirubinaemia caused by druginduced hepatotoxicity in early pregnancy. |
| As toxicity progresses, centrizonal hepatocellular injury may develop, manifesting as hepatocellular enzyme elevation and hyperbilirubinaemia. |
| As well as biliary atresia, there are many other causes of conjugated hyperbilirubinaemia. |
| It may induce haemolytic anemia, hyperbilirubinaemia and phototoxicity. |
| Many patients on ATZ experience indirect hyperbilirubinaemia, which causes social discomfort but does not necessitate a therapeutic change. |
| Severe hyperbilirubinaemia, or failure to respond to phototherapy, may require exchange blood transfusion. |
