| The division among progressive allies is a signal of the genomic politics to come. |
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| Molecular markers derived from cDNA and genomic DNA clones were from the tomato high-density linkage map. |
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| Their genomic structure is similar at a gross level, but has yet to be compared comprehensively in detail. |
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| Both the cases had no consistent abnormality confirmed by genomic karyotyping. |
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| Only full-length genomic and cDNA clones, including genes with in-frame stop codons, were analyzed. |
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| However, translation of genomic research discoveries to improved clinical outcomes can occur only with an informed professional workforce. |
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| We performed PCR on wild-type mouse genomic DNA to amplify sequences flanking transposon insertion sites for use as probes. |
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| Genes were amplified from genomic yeast DNA using specific oligonucleotides and the polymerase chain reaction. |
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| Nutritional genomics is the application of high throughput functional genomic technologies in nutrition research. |
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| Herman is looking for new genetic, genomic, and proteomic methods to improve protein, oil, and nutritive value in soybeans. |
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| To identify expressed sequences, 16 kb of genomic DNA flanking the proviral integration site was sequenced and compared to genetic databases. |
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| Conceivably, the disruption of intrinsic chromatin states by alien DNA insertion could affect genomic stability in myriad ways. |
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| Molecular access to the sda gene was via the sda HZ.P1 mutation by the method of plasmid rescue of genomic DNA flanking the transposon insertion. |
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| If evidence is to be found to support such a hypothesis, it will be by examining patterns of genomic organization. |
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| In contrast the data do suggest that gene transcript level in the hybrid triploids is related to genomic dosage. |
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| In plants, large genomic DNA clones from one species were mapped by FISH on chromosomes from related species. |
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| We used it at several steps in our cloning procedure including recovery of the genomic fragments for shotgun cloning and eventual sequencing. |
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| In the normal lymphoid ontogeny, genomic recombinations occur in a tightly regulated sequence and require an enzyme called recombinase. |
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| The gene expression biomarkers of caloric restriction can also be used to develop pharmaceuticals targeted to its genomic effects. |
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| Epigenetic regulation in aging mammals can be quantitatively measured using genes subject to X chromosome inactivation and genomic imprinting. |
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| In mammals, methylation is required for essential developmental programs including X chromosome inactivation in females and genomic imprinting. |
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| For comparison, we sequenced genomic DNA from the stock used to generate the mutants. |
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| We sequenced genomic DNA from heterozygous animals in an attempt to identify the remaining mutations. |
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| High-level amplification was revealed by comparative genomic hybridization. |
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| The origin and genomic dispersion of several microsatellites might have anteceded species diversification. |
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| The ancient Siberian demonstrates genomic signatures that are basal to present-day western Eurasians and close to modern Native Americans. |
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| This divergence may be explained by genomic differences between these two species that are reflected in their relative robustness. |
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| Cell lines were maintained as directed by the source, and DNA isolations were performed using Wizard genomic DNA purification. |
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| The accumulation of viscous polysaccharides in the mycelia of S. commune often interferes with genomic DNA isolations. |
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| EcoRI sites determined by restriction mapping are shown as tick marks on the genomic clones and as half-tick marks below the top line. |
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| Are there particular enzymes that could be targeted to reduce genomic instability, active-site switches to throw on or block? |
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| This approach has already been used successfully to saturate different genomic regions of sugar cane, barley and wheat. |
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| Our method naturally weights and combines into reliable predictions genomic features only weakly associated with interaction. |
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| Exposure to ionizing radiation or environmental mutagens and carcinogens may lead to genomic instability. |
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| Accumulating data from genomic databases will soon provide the solution to this evolutionary puzzle. |
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| The chromosomal location, patterns of genomic dispersion, and copy numbers of its tandemly arranged units varied between the species. |
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| Once achieved, the targeting of genomic regions for varietal improvement would be possible through marker-assisted selection. |
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| Single-locus genomic sequences can help determine if the organism is a subspecies or part of a superspecies. |
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| Such comparative analyses can provide important information about the concordance of genomic, functional, and evolutionary classifications. |
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| To generate a partial mtDNA genomic library, mtDNA was isolated according to Barriga Sosa et al., followed by CsCl isopycnic centrifugation. |
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| We noted a number of weaknesses and inconsistencies in the genomic analyses, not unexpected from a field in its infancy. |
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| Several explanations have been proposed for the acquisition of genomic imprinting in eutherian mammals. |
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| Strawberry genomic DNA was extracted from achenes removed from W1-stage strawberry fruits as described previously. |
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| Additionally, the ability to detect this signature at a genomic level in the human lineage is complicated by other factors. |
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| In the long run, I fully expect gene therapy and antisense to fix what can be fixed at the genomic level. |
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| In conclusion, the application of AI to deciphering genomic information is only just beginning. |
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| Some genomic details are already posted on the World Wide Web for use by researchers everywhere. |
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| Progress made by the genomic community has led to what is called microarray technology. |
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| An important objective of the genomic approach is the understanding of the most basic mechanisms of physiology. |
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| Let's talk about some of these revolutionary genomic initiatives, beginning with chemical genomics. |
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| With the genomic revolution, new tools have become available to study human diversity at the DNA level. |
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| The project produced many remarkable insights into the complexities and contrarieties of genomic structure. |
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| In rice, this analysis has been employed to detect genomic regions associated with several traits exhibiting complex inheritance. |
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| These data indicated that the cloned genes represented the genomic loci that were altered in the original rye strains. |
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| The data included results of genomic typing at polymorphic loci at or near genes of the autoimmune inflammatory response. |
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| Samples were sonicated for 5 sec four times to shear genomic DNA and reduce viscosity. |
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| For most elements with poly tails in the genomic sequence, the canonical AATAAA polyadenylation signal can be found upstream. |
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| Few detailed studies of large contiguous barley genomic sequences have been published. |
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| But recently, new forms of genomic variation have been appreciated above and beyond single nucleotide polymorphisms. |
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| Analysis of fugu genomic sequences revealed the presence of five NgR-related genes. |
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| Only genomic DNA, however, can help scientists understand the functional differences between extinct and living species. |
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| Isochores were defined as long genomic segments that are fairly homogeneous in their guanine and cytosine composition. |
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| Major chromosomal rearrangements are often found in transformed genomes, suggesting that T-DNA insertion either requires or causes genomic instability. |
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| Because synteny had been previously established, it was possible to evaluate whether homologous genomic regions were involved in regulation of expression of the same genes. |
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| The upper band is amplified genomic DNA containing the intronic sequence. |
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| This rationale can be used to identify genomic regions or genes harboring mutations that maintain reproductive barriers between diverging populations. |
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| Theoretical studies suggest that the joint effects of selection and linkage may lead to broadscale patterns of genetic variation in different genomic regions. |
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| Acquisition of genomic aberrations, a hallmark of malignancy, in regions of the genome that contain hemopoietic cell regulatory genes may also contribute to lymphomagenesis. |
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| A plasmid containing this 3.1 kb of wild-type genomic DNA was cotransfected with a trp1 plasmid into protoplasts isolated from an auxotrophic thn1 mutant strain. |
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| Indeed, increasingly, it is clear that the variability in phenotype and biological behavior of gliomas is a function of genomic and proteomic variability. |
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| This may create political pressures for increased government involvement in the application of genomic knowledge that could have spillovers to other sectors of the economy. |
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| A total of four 150-mm plates that contained 31,500 plaques from the unamplified A. aegypti genomic library were screened under the conditions described above. |
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| Eighteen candidate clones from the genomic library were digested with a series of restriction enzymes, Southern blotted, and hybridized with the same probe. |
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| It is difficult to identify a gene from a genomic sequence unless a messenger RNA from of the gene has been previously isolated, according to Fannon. |
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| Direct sequencing of this fragment showed that it was colinear with the genomic sequence of PMCHL1, indicating that it corresponded to unspliced transcripts of that gene. |
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| Mark was told by his geneticist that, given her genomic configuration, Jennifer was unusually verbal, mobile, and independent. |
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| The unequal expression in mammals of some maternally and paternally derived genes known as genomic imprinting reduces the masking benefits of diploidy. |
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| These short cDNA fragments are then compared with genomic databases. |
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| Exons were assigned by comparison of messenger RNA and genomic sequences. |
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| These latter bands were reconfirmed by multiple isolations and PCR-amplifications of VMA1 from genomic DNA initially derived from single cell cultures. |
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| Many aspects of plant biology are relevant to this challenge, and modern genomic biology will be essential to complement traditional physiological and agronomical studies. |
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| Firstly, we will establish the genomic interacting landscape of landmark drugs including etoposide, camptothecin and cisplatin using Drug-Seq. |
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| The test contains information on all of the key genetic markers needed for the USDA-AIPL genomic evaluation. |
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| They differ from the other kits in that they use transposomes to fragment the genomic DNA, whereas the other platforms use ultrasonication. |
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| The researchers chose genomic DNA sequences that code for conglutin genes as targets for detecting lupin. |
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| Macrorestriction polymorphism of genomic DNA determined by PFGE revealed the presence of two pulsotypes among the nine study isolates. |
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| Thus, processes of hypoaneuploidy could affect genomic stability producing this variation in number of loci. |
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| Moreover, two genomic regions strongly responded to selection for thermal tolerance in interlatitudinal crosses. |
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| A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling. |
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| Telomeres are repetitive DNA-protein complexes that protect the ends of linear chromosomes and maintain genomic stability. |
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| Evolution and phylogenetic information content of mitochondrial genomic structural features illustrated with Acrodont lizards. |
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| Syntenic relationships between genomic profiles of fiber-induced murine and human malignant mesothelioma. |
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| Results demonstrate that this genomic instability is a part of a ROS induced mutator phenotype in the testis that leads to tumorogenesis. |
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| This all added up to one in three patients saved from chemotherapy through the genomic transcriptional profiling. |
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| Transposons are parasitic DNA elements that when activated can insert into new genomic locations, leading to genome instability. |
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| A cosmid clone, pOK40, which complements the mutant K818, was isolated from a genomic library of the parent strain. |
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| Craig Venter Institute, a not for profit genomic focused research institute, and Founder and CEO of Synthetic Genomics Inc. |
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| Off-target deamination by AID results in nucleotide substitutions and genomic rearrangements in B lymphocyte tumours. |
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| Neonatal exposure to diethylstilbestrol alters expression of DNA methyltransferases and methylation of genomic DNA in the mouse uterus. |
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| Cytogenetical analysis in paraffin-embedded fetoplacental tissue using comparative genomic hybridization. |
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| ZymoGenetics identified the novel cytokine family containing Interleukins 28A and 29 from human genomic sequence. |
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| The genomic and molecular studies demonstrated multiple alterations in the steroidogenic machinery of theca cells from PCOS women viz. |
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| Additionally, genomic analysis has found that Berber and other Maghreb communities are defined by a shared ancestral component. |
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| Its small genome, rapid life cycle, small size, and large number of mutants and genomic resources make it an ideal angiosperm for plant research. |
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| Craig Venter Institute, a not-for-profit genomic research organization, announced today they have hired Nicole DeBerg as Chief Operating Officer. |
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| Scientists hope Crispr might also be used for genomic surgery, as it were, to correct errant genes that cause disease. |
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| Individuals are actually superorganisms both in terms of function and genomic content. |
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| The results of the tests of genomic ancestry are quite different from the self made estimates of European ancestry. |
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| The consortium was able to successfully develop and test a new vaccine for Lassa fever in 120 days, starting only from genomic data on the virus. |
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| Cartesian products based on this technology are experiencing rapid sales growth in the high throughput screening, functional genomic and combinatorial chemistry markets. |
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| Most unigenes in the set are likely to be transcribed from separate genomic loci, however some also represent divergent alleles or homeologs at the same genomic locus. |
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| Sequence analysis and editing for bisulphite genomic sequencing projects. |
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| Combining Roche's expertise in genetics, genomics and proteomics with CombiMatrix's Biochip Platform will not only speed up but also shape the future of genomic research. |
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| Pangene Corporation announced the breakthrough development of robot automated gene cloning which captures cDNA, genomic DNA, and gene family clones. |
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| Epstein-Barr virus genomic sequences and specific antibodies in cerebrospinal fluid in children with neurologic complications of acute and reactivated EBV infections. |
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| By using blocking DNA and pre-annealing to block homoeologous sequences, labeled genomic DNA probes from one parent could not hybridize to chromosomes from the other one. |
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| Similar to other RNA viruses, RVAs show high genomic diversity, which is generated primarily through point mutations, reassortment, rearrangement, and recombination events. |
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| The discovery of these influential genes that determine the architecture of plants was a surprise that created a whole new subfield of plant genomic studies. |
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| In fact, these subtelomeric regions are sites of marked genomic plasticity and appear to serve as nurseries for generating new genes and enhancing genetic diversity. |
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| The preferred approach is genotyping, which is commonly performed by macrorestriction digestion of genomic DNA with a rare-cutting restriction endonuclease. |
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| Each genomic DNA was having one or few sites for restriction enzymes. |
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| In the 2010s, genomic testing of living populations has located archaic admixture of modern humans outside of Africa with Neanderthals and Denisovans. |
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| Case reports of returning travelers, and sequence data from sylvatic DENV strains account for most of what is known at the genomic level regarding DENV circulating in Africa. |
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| All strains were positive for fcpA, tcpI, acfB, toxT, ctxA, zot, and ToxR genes, as well as for the O139-specific genomic DNA in DNA probe or PCR assays. |
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| TimeLogic's DeCypher systems are pre-programmed with mathematical algorithms that allow scientists to extract and analyze massive amounts of genomic data very rapidly. |
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| Compugen's in-house molecular biology laboratories provide validation of its methodologies and also conduct original genomic and proteomic research. |
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| Seo and Shneiderman present uses for dendrograms in exploring high-dimensional hierarchical cluster structures in the context of genomic microarray analysis. |
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| Arabidopsis thaliana is a leading system to study the regulatory roles of small RNAs because of the abundance of genetic, genomic and epigenomic resources. |
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| Synthetic nucleic acids are used in the analysis of nucleic acid samples with unknown sequences and in virtually every genomic and genetic analysis technique. |
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| They drew a phylogenetic tree based on the sequences of these Indian swine isolates, and genomic sequences of HEV isolates from humans and animals. |
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| The role of genetic and genomic attributes in the success of polyploids. |
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| Beyond the chemical fingerprint, the genetic, genomic and proteomic fingerprints of plants, plant mixtures or plant extracts can now be determined using specific test systems. |
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| Furthermore, no statistically significant association of arsenic exposure was observed in relation to global methylation levels across autosomes on a genomic scale. |
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| We developed a system for rapid determination of viral RNA sequences whereby genomic sequence is obtained from cultured virus isolates without subcloning into plasmid vectors. |
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