What is another word for most depressant?

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Contexts (chiefly of a drug) Superlative for reducing functional or nervous activity Superlative for feeling or bringing no joy Adjective ▲ (chiefly of a drug) Superlative for reducing functional or nervous activity dreamiest tranquilest peacefullest mildest placidest calmest quietest gentlest comfortablest laziest lightest balmiest benignest tenderest mellowest most sedative most narcotic most soothing most relaxing most calmative most anodyne most lenitive most comforting most ataraxic most ataractic most palliative most restful most reassuring most analgesic most soporific most reposeful most demulcent most romantic most therapeutic most relieving most emollient most alleviatory most alleviative most mitigatory most paregoric most mitigative most carefree most leisurely most anaestheticUK most anestheticUS most indulgent most serene most untroubled most halcyon most undisturbed most temperate most chilled most relaxed most consolatory “Alcohol has a stronger and faster depressant effect on the brain, causing memory loss and problems with coordination.” Adjective ▲ Superlative for feeling or bringing no joy saddest miserablest unhappiest glummest gloomiest forlornest mournfullest dolefulest lowest woefullest wretchedest sorriest morosest droopiest baddest sombrestUK somberestUS sullenest dreariest dourest mopiest blackest heaviest most joyless most depressed most dejected most despondent most downcast most disconsolate most melancholy most sorrowful most crestfallen most blue most woebegone most heartbroken most melancholic most inconsolable most dispirited most heartsick most brokenhearted most dismal most heartsore most cheerless most lugubrious most depressing most mirthless most humorlessUS most humourlessUK most saturnine most saddening most low-spirited most heavy-hearted most down in the mouth most down in the dumps Find more words! 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