| At the same time, the cartilage deep to this collar begins to degenerate and calcify. |
| In severe case, the bone structure may change and ligaments may calcify, with resulting impairment of muscles and pain. |
| Strategies evolve to counter one another, and better to encourage experimentation than to calcify tradition by fiat. |
| Over time, the minerals in our saliva make the plaque harden and finally calcify. |
| Other collagenous tissues, such as dermis, tendon, and ligament, do not normally calcify, even though bathed by the same body fluids as bone. |
| If plaque is not regularly removed the flora evolves, and plaque may calcify, forming calculus. |
