| A chief difficulty in arguing for macroevolution by mutations is the fact that most expressed mutations are either lethal or semi-lethal. |
| Creationists are usually more careful about distinguishing between microevolution and macroevolution at this point. |
| Creationists argued that while Gould's proposed mechanism could explain speciation, it could not explain macroevolution. |
| Instead, they say that macroevolution is nothing more than microevolution played out over long periods. |
| Similarly, microevolutionary explanations may not provide a sufficient account of macroevolution, even if such reductionism were justifiable in principle. |
| In antievolution literature, vertical change equates with macroevolution, or evolution above the species level. |
