“Once built, they attached the new hapten molecules to carrier proteins, mixed them with adjuvant, injected the results into mice and waited.”
“It may be that both hapten formation and cell damage are involved, and the role may be different with different health products.”
“Their specificity could be related to particular defined groups on the antigen and evaluated quantitatively with precipitin reactions and hapten inhibition of precipitation.”
“It is likely that low-molecular-weight agents act as haptens, combining with human proteins in the respiratory tract to become complete immunogens.”
“Supporting this is the discovery by Vojdani et al., who reported that some individuals develop allergic antibodies to haptens formed in response to MTBE binding to albumin.”
“The bound microparticle complexes are then incubated with antidetection hapten alkaline phosphatase conjugate, which binds to the detection haptens.”