| It is likely that low-molecular-weight agents act as haptens, combining with human proteins in the respiratory tract to become complete immunogens. |
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| Supporting this is the discovery by Vojdani et al., who reported that some individuals develop allergic antibodies to haptens formed in response to MTBE binding to albumin. |
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| The bound microparticle complexes are then incubated with antidetection hapten alkaline phosphatase conjugate, which binds to the detection haptens. |
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| This phenomenon is clinically well known as anergy to tuberculin or other immunogenic haptens after subcutaneous injections. |
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| Toxic metabolites form haptens with tissue proteins and produce neoantigens, such as the formation of reactive hydroxylamines from sulfonamides. |
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| Mercuriation of nucleic acids is performed after ISH is completed using haptens with SH groups that bing the mercury. |
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| It is also possible that methamphetamines alter self-proteins, making them immunogenic or creating haptens. |
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| Filaggrin deficiency confers a paracellular barrier abnormality that reduces nflammatory thresholds to irritants and haptens. |
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| Reactive intermediate products which form as a result of metabolism in the liver or in another place act as haptens and bind to high molecular weight proteins. |
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