| Numerous treatments such as analgesic medications, muscle relaxants, antidepressants, and triptans had shown little or no effect. |
| The class of triptans include sumatriptan, rizatriptan, zolmitriptan, naratriptan, almotriptan, eletriptan, and frovatriptan. |
| Using vasoconstrictors such as ergotamine and the triptans in the presence of focal ischaemia is a theoretical concern. |
| Triptans like Sumatriptan and Zolmitriptan are also available as nasal sprays whereas rizatriptan and zolmitriptan are available as tablets that dissolve in the mouth. |
| The triptans are specific and selective serotonin agonists that block serotonin receptors and the resultant neurogenic inflammation. |
| Naratriptan, almotriptan, and zolmitriptan are among the triptans approved in the United States. |
