| Numerous treatments such as analgesic medications, muscle relaxants, antidepressants, and triptans had shown little or no effect. |
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| Using vasoconstrictors such as ergotamine and the triptans in the presence of focal ischaemia is a theoretical concern. |
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| The triptans are specific and selective serotonin agonists that block serotonin receptors and the resultant neurogenic inflammation. |
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| The class of triptans include sumatriptan, rizatriptan, zolmitriptan, naratriptan, almotriptan, eletriptan, and frovatriptan. |
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| Naratriptan, almotriptan, and zolmitriptan are among the triptans approved in the United States. |
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| Four triptans are registered for use in South Africa, namely sumatriptan, rizatriptan, naratriptan and zolmitriptan. |
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| Specific triptans include naratriptan, rizatriptan, sumatriptan, zolmitriptan, almotriptan, frovatriptan and eletriptan. |
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| Triptans work by vasoconstricting the meningeal blood vessels. |
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| Triptans like Sumatriptan and Zolmitriptan are also available as nasal sprays whereas rizatriptan and zolmitriptan are available as tablets that dissolve in the mouth. |
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