It is known that induction of telomere shortening leads to the extinction of yeast clones similar to a senescent phenotype. |
The telomere is but one of the factors in the aging process, and research remains intense in this area. |
Such a widespread conservation of telomeric silencing among eukaryotes suggests that it is fundamental to telomere function. |
All transfectants lacked detectable telomerase activity, showed progressive telomere shortening and ultimately arrested and died. |
These two genes are tightly linked to the left telomere of the X chromosome. |
In nature, a chromosome can be lengthened by the enzyme telomerase, which adds new TTAGGG sequences to the end of the telomere. |