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What is smooth endoplasmic reticulum?

What is smooth endoplasmic reticulum? Here are some definitions.

Noun
  1. (cytology) The region of the endoplasmic reticulum that is not occupied by ribosomes and is involved in the formation of distinct lipids.
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Examples
Aggregation of smooth endoplasmic reticulum in the supranuclear region has also been described in the brush cells of the striped snake.
All metabolic reactions occur in the smooth endoplasmic reticulum except conversion of CHOL to PREG, which occurs in the inner mitochondrial membrane.
Ifosfamide is activated by metabolism in the liver by the mixed function oxidase system of the smooth endoplasmic reticulum.

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