Ifosfamide is activated by metabolism in the liver by the mixed function oxidase system of the smooth endoplasmic reticulum. |
The cytoplasm also contained some mitochondria, granular endoplasmic reticulum, single ribosomes and polyribosomes, and Golgi complexes. |
Aggregation of smooth endoplasmic reticulum in the supranuclear region has also been described in the brush cells of the striped snake. |
It is also present in smaller amounts in the membranes of the mitochondria and endoplasmic reticulum within the cells. |
Methyl viologen also affects electron-transducing reactions in the endoplasmic reticulum and in mitochondria. |
Slower-mobility products result from improper processing in the endoplasmic reticulum, which is likely the result of misfolding. |