It was found that hemizygous disruption of the XRCC3 gene was sufficient to increase the point mutation frequency. |
High selective discrimination against point mutation of bacteria at hot-spot region was observed. |
If no deletion is found, a point mutation is probable. |
Arrows indicate the position of the point mutation and the corresponding nucleotide on the wild-type sequence. |
The compound did not induce point mutation in the Fluctuation assay, and did not demonstrate gene convertogenic activity in yeast cells. |
So tell me how a simple point mutation changes the information content of the gene. |