High selective discrimination against point mutation of bacteria at hot-spot region was observed. |
The compound did not induce point mutation in the Fluctuation assay, and did not demonstrate gene convertogenic activity in yeast cells. |
In humans, you can get a single point mutation, and a vaccine that's 99.99percentt related won't protect you. |
To introduce a point mutation the gene must be cloned, the desired point mutation must be generated within that clone, and an I-SceI site must be inserted. |
If no deletion is found, a point mutation is probable. |
So tell me how a simple point mutation changes the information content of the gene. |