Arrows indicate the position of the point mutation and the corresponding nucleotide on the wild-type sequence. |
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So tell me how a simple point mutation changes the information content of the gene. |
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We can only estimate the relative expansion slippage rates and contraction slippage rates compared to the point mutation rate. |
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The compound did not induce point mutation in the Fluctuation assay, and did not demonstrate gene convertogenic activity in yeast cells. |
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In humans, you can get a single point mutation, and a vaccine that's 99.99percentt related won't protect you. |
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The mutation responsible for imidazolinone tolerance is due to a point mutation of a single nucleotide in the AHAS gene. |
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High selective discrimination against point mutation of bacteria at hot-spot region was observed. |
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In this study, we have introduced two inter-subunit disulfide bridges with one point mutation. |
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It was found that hemizygous disruption of the XRCC3 gene was sufficient to increase the point mutation frequency. |
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To introduce a point mutation the gene must be cloned, the desired point mutation must be generated within that clone, and an I-SceI site must be inserted. |
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Asparaginase did not induce point mutation in the bacterial assay and was not clastogenic in the chromosomal aberration assay. |
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If no deletion is found, a point mutation is probable. |
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Their dystrophin gene has a point mutation in the splice receptor site of intron 6 which leads to the deletion of exon 7 in the mRNA, to a frame shift, and a premature stop codon. |
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The dystrophic mouse: Most of the experiments with this aim have been performed with one kind of laboratory animal, the dystrophic mdx mouse, which has a point mutation at base pair 3,185 in exon 23 of its dystrophin gene. |
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I've studied three-letter organisms which by point mutation saltate into others, as yam into ram. |
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Schemes and plate assays of point mutation constructs. |
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In the meantime, the reading frame could be corrected in in-vitro muscle preparations from six other patients who had different deletions and also a point mutation. |
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The DNA strand of the chimeric oligonucleotide is perfectly complementary to the correct gene sequence at the point mutation site of the gene, while the RNA portion is perfectly complementary to the mutant sequence. |
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As the structure of the dystrophin gene is known in all details, it is already possible to predict which exon would have to be skipped in order to restore the reading frame after a defined deletion or point mutation. |
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A method of identifying the presence of a cancer in a subject, comprising detecting the presence of a point mutation in the c-raf-1 gene of the subject. |
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Imidazolinone tolerance in Clearfield rice varieties CL IMINTA 1 and CL IMINTA 4 is due to a point mutation of a single nucleotide in the Als gene. |
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Data files are now compiled which will allow the prediction of the clinical course of a Duchenne or Becker muscular dystrophy based on a defined deletion, duplication or point mutation. |
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