| The respiration is at first accelerated by a dose of physostigmine, but is afterwards slowed and ultimately arrested. |
| But since physostigmine could be isolated only from the Calabar bean, the drug was not readily available. |
| His synthesis of physostigmine, found in the Calabar bean, or Physostigmavenenosum, yielded a treatment for glaucoma. |
| Early in his career Julian attracted attention for synthesizing the drug physostigmine, used to treat glaucoma. |
| The symptoms of anticholinergic overdose may be treated with physostigmine in a dosage of 1 to 2 mg given intramuscularly or intravenously at 20-minute intervals. |
| After subcutaneous or local application, a dilatation neutralised by physostigmine in moderate doses. |
