| The most significant treatment-related effect was a decrease in cholinesterase activity of plasma, RBC, and brain. |
| If the memory loss is severe enough to warrant a diagnosis of dementia, then cholinesterase inhibitor therapy would be indicated. |
| The cholinesterase inhibitor tacrine is used rarely because of potential liver toxicity and the need for frequent laboratory monitoring. |
| This product, upon repeated or prolonged use, may cause cholinesterase inhibition. |
| Atropine is antidotal and should be administered only if symptoms of cholinesterase inhibition are present. |
| The symptoms of cholinesterase inhibition are nausea, vomiting dizziness, tremors, salivation and constricted pupils. |
