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What is pathogenesis?

What is pathogenesis? Here are some definitions.

Noun
  1. The origin and development of a disease.
  2. The mechanism whereby something causes a disease.
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Examples
The precise etiology and pathogenesis of laryngeal amyloidosis remain unknown.
The possibility that a cytotoxin may play a role in the pathogenesis of EPEC infection had been suggested.
The eosinophil is believed to be the principal effector cell for the pathogenesis of allergic inflammation.
Although the exact cause of acne is unclear, its pathogenesis involves many factors that are interrelated.
There is broad consensus that cognitive deficits play a crucial role for both the pathogenesis and prognosis of schizophrenic psychoses.
The pathogenesis of arterial thrombotic disease involves multiple genetic and environmental factors related to atherosclerosis and thrombosis.

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