| The second mechanism of TCA cardiotoxicity involves the blockade of norepinephrine uptake at the adrenergic presynaptic endings. |
| Many antidepressants inhibit serotonin or norepinephrine reuptake or both to achieve their clinical effect. |
| When you're under stress your adrenal glands produce the hormones cortisol, norepinephrine, and adrenaline. |
| In addition to their effects as neurotransmitters, norepinephrine and epinephrine can influence the rate of metabolism. |
| Serotonin is a vasoconstrictor and uses agonists, such as ADP, epinephrine, and norepinephrine, to promote platelet aggregation. |
| Thus, sympatholytics interfere with the part of the nervous system that uses norepinephrine to raise blood pressure. |
