| Abnormal hemorrhage, hyperbilirubinemia and oliguria are late findings. |
| Despite these recommendations, infants continue to present with severe hyperbilirubinemia during or after their initial hospitalization. |
| Hemoglobinemia, hemoglobinuria and subsequent hyperbilirubinemia are usually detectable. |
| Critical hyperbilirubinemia is uncommon but has the potential for causing long-term neurological impairment. |
| Furthermore, clinical assessment of jaundice is inadequate for diagnosing hyperbilirubinemia. |
| An infant who presents with severe hyperbilirubinemia or who progresses to severe hyperbilirubinemia despite initial treatment should receive immediate intensive phototherapy. |
