| These mediators and the related tissue injury prolong pain and hyperalgesia. |
| Neurogenic inflammation is a process by which sensory nerves may secrete inflammatory mediators, resulting in hyperalgesia and inflammation. |
| Combined action of vasoactive amines and bradykinin mediates allergen-evoked thermal hyperalgesia in rats. |
| Pre-emptive analgesia is preferable to reactive analgesia when conducting surgical procedures, reducing or preventing hyperalgesia, allodynia, or wind-up. |
| Inhibition of inflammatory hyperalgesia was also demonstrated in rats. |
| When patients receive narcotics for long periods, they can even become more sensitive to pain, a condition called hyperalgesia. |
