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What is drug abuse?

What is drug abuse? Here are some definitions.

Noun
  1. Misuse of, or overindulgence in, drugs; substance abuse. [from 20th c.]
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For some, alleviation of the drug abuse problem will serve to reduce related criminal behavior.
This in turn led to a dependence on them, which was then followed by drug abuse.
The Schmidts are not perceptive, so they did not notice the warning signs of drug abuse.
Adolescent drug abuse co-occurs with other clinical problems with alarming frequency.
The soaring burglary rate is coupled with a drug abuse epidemic that adds more violence to even the simplest of burglaries or muggings.
The city is full of beer bars and this group of operators and their staff have had many problems with drug abuse and dealing.

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