| Zebra fish and mammals are separated by a long evolutionary distance and yet, surprisingly, the first step in the regeneration process, the dedifferentiation of heart muscle cells, occurs in mammals as well. |
| This dedifferentiation disrupts further co-ordinated development which ultimately causes seed abortion. |
| Researchers have also been able to generate cardiac stem cells for the treatment of certain forms of heart disease through the process of dedifferentiation, in which mature heart cells are stimulated to revert to stem cells. |
| Wilms' tumor 1 gene expression in hepatocellular carcinoma promotes ceil dedifferentiation and resistance to chemotherapy. |
| This probably reflects the presence of stem cells in the nail bud rather than cell dedifferentiation. |
| Cardiac stem cells can be derived from mature cardiomyocytes through the process of dedifferentiation, in which mature heart cells are stimulated to revert to a stem cell state. |
