When levodopa is administered orally it is rapidly converted to dopamine by decarboxylation in peripheral tissues so that only a small portion of a given dose is transported unchanged to the central nervous system. |
Acetoacetate can undergo spontaneous decarboxylation to acetone, or be enzymatically converted to b-hydroxybutyrate through the action of b-hydroxybutyrate dehydrogenase. |
Some of the most common and promising processes of conversion of renewable lipids into usable fuels is through hydrotreating and decarboxylation. |
Similarly, histamine arises in many tissues by the decarboxylation of histidine, which in excess causes constriction or dilation of various blood vessels. |
Carbidopa inhibits decarboxylation of peripheral levodopa. |
Other metabolites resulting from oxidative decarboxylation are partly eliminated via the lung as carbon dioxide. |