| It is through changes in the production of cyclins during the cell cycle that the activity of the genes controlling it are themselves regulated. |
| This enzyme and others like it link up with proteins called cyclins, and together these molecules push a cell to start dividing. |
| In his Nobel lecture, Hunt lauded the simple, but brilliant, experiments of Ruderman and Katherine Swenson, who were the first to show that cyclins bring about cell division. |
| Proteasome degradation of cyclins involved in cell cycle regulation has been well documented. |
| The accumulation and breakdown of cyclins is an essential step in cell division. |
| Numerous studies from different laboratories have shown an extensive functional overlap between these two cyclins. |
