Most folks who know about drug discovery will tell you about the lessons of thalidomide as they relate to the chirality of drugs. |
Test results demonstrate that the methods are capable of differentiating between potential isomers and the product, and show that none of the chemical transformations cause a loss of chirality. |
All of this is achieved without switching the chirality of the catalyst. |
The technique might also be used to template the growth of complex molecular structures with novel architecture and chirality. |
Such isomers are called enantiomers and molecules that have enantiomers are said to be chiral or to show chirality. |
In most cases, the biaryl axis is configurationally stable and represents an additional element of chirality. |