Most folks who know about drug discovery will tell you about the lessons of thalidomide as they relate to the chirality of drugs. |
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In most cases, the biaryl axis is configurationally stable and represents an additional element of chirality. |
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Barron now suggests extending the definition of chirality to include time-reversal as well as dissymmetry. |
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Such isomers are called enantiomers and molecules that have enantiomers are said to be chiral or to show chirality. |
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The technique might also be used to template the growth of complex molecular structures with novel architecture and chirality. |
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Thus Pasteur established the principle of chirality as a fundamental property of organic chemical structure. |
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All of this is achieved without switching the chirality of the catalyst. |
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Another aspect arising from the macroscopic chirality of gel networks refers to applications in material science such as sensors or switches, he told Reactive Reports. |
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The implications of any differences in the chirality, chemical form, and impurity profile between the compound used in the nonclinical studies and the product to be marketed shall be discussed. |
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We have recently demonstrated that a polarization hologram could be recorded and that polarization information could be recovered, for example we separated light according to its chirality. |
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In 1993, Division II also launched the CHiral2 research initiative with a total budget of CHF 9.8 million in order to foster research into chirality. |
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Consistent with genuine specimens, the etched shells accurately exhibit dextral chirality, or right-handedness. |
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All twining plants exhibit handedness, which scientists term chirality, but botanists believe it has nothing to do with which hemisphere they grow in, but rather is an inborn tendency that varies by species. |
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Unfortunately, particle physics predicts that any particle that has chirality cannot have mass, so a massive chiral fermion is a contradiction in terms. |
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And, although the pharmacological significance of chirality was evident in the 1930s, separating the mixtures was until recently too painstaking to be practical. |
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That is why chirality rules living systems. |
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Although knot identification and chirality can be associated with an individual, most people believe that this chirality is a direct correlation to their handedness. |
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One of our strengths in this area is the development of new technological routes to pharmaceutical or agrochemical molecules or intermediates, led by our capabilities in chirality, phosphorus chemistry and catalysts. |
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Test results demonstrate that the methods are capable of differentiating between potential isomers and the product, and show that none of the chemical transformations cause a loss of chirality. |
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In olfaction, these features might be chemical species, chirality, concentration, location, stationariness, or rate of encounter. |
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Philae includes experiments to test a molecule's symmetrical construction, or chirality. |
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We will explore how the sense of helical chirality of these molecules can be switched just with light. |
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It is important to note that the small tide-forming forces of the Moon and Sun create the chirality of plants. |
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The influences of the chirality on the scattering are investigated. |
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Stereospecificity can be achieved by rotational restrictions that store any substrate chirality in the intermediate triplet biradical and yield a stereospecific product. |
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It is noteworthy that AveF and DnrU also control different opposite chirality in avemectin and daunorubicin pathways, but both of them are present in a same group. |
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Chirality describes the handedness of a molecule that is observable by the ability of a molecule to rotate the plane of polarized light either to the right or to the left. |
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