A tRNA molecule is a single nucleotide chain with several helical regions and a loop containing three unpaired nucleotides, called an anticodon. |
These quantities indicate quite clearly the general effect of codon binding on the anticodon structure and fluctuations. |
The E Site is the exit site for the tRNA anticodon once it deposits its amino acid from the cytoplasm onto the growing polypeptide chain. |
Their position between the second and third base of the anticodon is conserved, which also implies evolutionary age. |
Thus, any mRNA codon that happens to be on the ribosome at any one time will solicit the binding only of the tRNA with the appropriate anticodon, which will align the correct amino acid for addition to the chain. |
The researchers changed the anticodon in their new tRNA to match up with the UAG stop codon instead of the codon for glutamine. |