Neoplastic cells showed a high degree of anaplasia, high nucleus-to-cytoplasm ratio, usually one prominent nucleolus, partially condensed chromatin, and high mitotic index. |
The benign nature of this lesion was suggested by the lack of any mitotic activity, anaplasia, or dysplasia. |
We theorize that tumor anaplasia caused malignant myocytes to reexpress CK-MB and cTnT isoforms. |
Microscopically, the tumor cells were arranged in diffuse compact trabeculae, with variable degrees of anaplasia, and increased mitotic activity in the control group. |
Anaplasia is a loss of visible differentiation that can occur in advanced cancer. |
Cancer cells also tend to be less-well-differentiated than normal cells, a characteristic that is called anaplasia. |