| Cancer cells also tend to be less-well-differentiated than normal cells, a characteristic that is called anaplasia. |
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| Three classes of abnormal cell differentiation are dysplasia, metaplasia, and anaplasia. |
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| We theorize that tumor anaplasia caused malignant myocytes to reexpress CK-MB and cTnT isoforms. |
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| The benign nature of this lesion was suggested by the lack of any mitotic activity, anaplasia, or dysplasia. |
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| Neoplastic cells showed a high degree of anaplasia, high nucleus-to-cytoplasm ratio, usually one prominent nucleolus, partially condensed chromatin, and high mitotic index. |
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| Microscopically, the tumor cells were arranged in diffuse compact trabeculae, with variable degrees of anaplasia, and increased mitotic activity in the control group. |
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| Anaplasia is a loss of visible differentiation that can occur in advanced cancer. |
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