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What is an ameliorator?

What is an ameliorator? Here are some definitions.

Noun
  1. A person who, or thing which, ameliorates.
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Examples
He was not, however, quite in a condition to see the ameliorator clearly.
It enjoyed increased sales of Ceredist, an agent for treating spinocerebellar degeneration, as well as Sermion, a cerebral circulation and metabolism ameliorator.

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