| Formation of ROS occurs through several univalent reduction steps, yielding first the superoxide anion, then hydrogen peroxide and the hydroxyl radical, and finally water. |
| This autoamplification of singlet oxygen through versatile usage of tumor cell specific ROS chemistry finally leads to the inactivation of catalase. |
| Iron and copper are the transition metal ions that are involved in the catalytic process of ROS generation. |
| In a traumatic brain injury, cells release an excessive amount of an ROS known as superoxide into the blood. |
| Alcohol metabolism leads to hepatic oxygen deficits, adducts and ROS formation, and interaction between alcohol metabolites. |
| An imbalance between production of ROS and production of antioxidants results in oxidative stress. |
