| An imbalance between production of ROS and production of antioxidants results in oxidative stress. |
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| Iron and copper are the transition metal ions that are involved in the catalytic process of ROS generation. |
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| By contrast to the initial ROS burst, these subsequent bursts were coincident with increases in oxidase protein components, particularly gp 91 phox. |
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| Free radicals like ROS, RNS and lipid peroxidation products such as Malondialdehyde have been shown to induce pressure of c-fos and c-jun oncoproteins. |
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| Formation of ROS occurs through several univalent reduction steps, yielding first the superoxide anion, then hydrogen peroxide and the hydroxyl radical, and finally water. |
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| Sperm stimulators, such as pentoxifylline and L-carnitine, are antioxidants and ROS scavengers. |
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| Alcohol metabolism leads to hepatic oxygen deficits, adducts and ROS formation, and interaction between alcohol metabolites. |
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| If ROS damage is the cause of aging, one would expect to find changes in ROS levels when animals eat a calorie-restricted diet. |
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| Results demonstrate that this genomic instability is a part of a ROS induced mutator phenotype in the testis that leads to tumorogenesis. |
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| In a traumatic brain injury, cells release an excessive amount of an ROS known as superoxide into the blood. |
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| The scavenging activity of the extract on ROS was correlated to its protocatechuic acid content. |
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| This autoamplification of singlet oxygen through versatile usage of tumor cell specific ROS chemistry finally leads to the inactivation of catalase. |
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| One of the most common and important ROS is the superoxide anion. |
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| Fucoxanthin, derived from brown seaweeds, has shown anti-adipose capability through modulating the elevation of ROS, and down-regulation of lipid metabolism genes. |
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| Western blotting revealed that DPI and NAC attenuated the effect of TMF, suggesting that TMF induces ROS through the NOX2 pathway and regulates keratinocyte migration. |
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| Other intracellular sources of the generation of ROS include reactions involving cytochrome P450 enzymes, peroxisomal oxidases, and NAD H oxidases. |
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| However, the source or mechanism of ROS formation remains elucidative. |
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