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What is a CRISPR?

What is a CRISPR? Here are some definitions.

Noun
  1. (microbiology) Segments of bacteria and archaea DNA containing short repetitions of base sequences. [from 2002]
  2. (genetics) The CRISPR/Cas9 system, which functions to provide immunity to bacteria and archaea by finding a section of DNA and replacing it with an alternative.
  3. Any technique or process or system for editing genomes by laboratory use of the CRISPR/Cas9 system.
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Indeed, using Crispr in non-reproductive cells – somatic cells – could cure many diseases.
The vertical axis lists strains containing CRISPR spacers that target a bifibacterial prophage sequence.
The downside is that using Crispr on somatic cells is far more complex: humans have trillions of cells and many different cell types.
Scientists hope Crispr might also be used for genomic surgery, as it were, to correct errant genes that cause disease.
The stolen DNA pieces are stored in specific locations in the bacterial genome called CRISPR loci.
The NextGEN CRISPR technology, developed by a member of Transposagen's Scientific Advisory Board, is the first truly dimeric RNA-guided FokI nuclease.

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