| Table 1 gives a description of CRISPR regions in Streptococcus pneumoniae and viridans group streptococci. |
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| The majority of identified CRISPR loci are associated with a set of conserved protein-encoding genes termed cas. |
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| This limited the CRISPR system to its minimal functional components and thus illuminated its potential as a powerful genome editing tool. |
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| The vertical axis lists strains containing CRISPR spacers that target a bifibacterial prophage sequence. |
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| The NextGEN CRISPR technology, developed by a member of Transposagen's Scientific Advisory Board, is the first truly dimeric RNA-guided FokI nuclease. |
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| Crispr has been developed from a mechanism used by some bacteria to defend themselves against viruses. |
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| Thus far, Crispr is too new for any somatic cell editing therapy to have entered clinical trials. |
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| Indeed, using Crispr in non-reproductive cells – somatic cells – could cure many diseases. |
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| The downside is that using Crispr on somatic cells is far more complex: humans have trillions of cells and many different cell types. |
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| Scientists hope Crispr might also be used for genomic surgery, as it were, to correct errant genes that cause disease. |
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