| The mode of vagal activation changes between 2 and 5 ml ABT from vagotonic to vagolytic. |
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| Interestingly, this effect is reduced by vagotomy, vagolytic agents or gangliar blocking agents, i.e. by anti-cholinergic maneuvers. |
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| The vagolytic effect of pancuronium may be reduced in patients administered nitrous oxide together with sufentanil. |
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| This effect was interpreted as vagolytic response. |
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| The use of moderate doses of pancuronium or of a less vagolytic neuromuscular blocking agent should maintain stable lower heart rate and blood pressure. |
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