| The vagolytic effect of pancuronium may be reduced in patients administered nitrous oxide together with sufentanil. |
| Interestingly, this effect is reduced by vagotomy, vagolytic agents or gangliar blocking agents, i.e. by anti-cholinergic maneuvers. |
| The use of moderate doses of pancuronium or of a less vagolytic neuromuscular blocking agent should maintain stable lower heart rate and blood pressure. |
| The mode of vagal activation changes between 2 and 5 ml ABT from vagotonic to vagolytic. |
| This effect was interpreted as vagolytic response. |
